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Molecular dynamic analyses of GFAP structure. (a) Initial modeled structure of GFAP.Yellow internal cavity is the predicted drug-binding pocket. (b) Predicted binding pocket volume for。

Glial fibrillary acidic protein (GFAP) is the main component of intermediate filaments of the cytoskeleton of astrocytes. Over more than fouofgfapr decades of fundamental and applied studies,。

GFAP encodes the predominant intermediate filament protein present in mature astrocytes. The biological roles of this protein are described in the companion review (Messing and Brenner,。

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